The Wellcome Trust Sanger Institute is a world leader in genomic research, with an expanding scientific programme dedicated to understanding gene function in health & disease.
The Wellcome Trust Sanger Institute, based south of Cambridge, is one of the world’s leading genomic research centres funded primarily by the Wellcome Trust. Our mission is to use genome sequences to advance understanding of the biology of humans and pathogens in order to improve human health.
The Institute conducts research in four thematic areas – human genetics, pathogen genetics, model organism genetics and informatics. Building on its expertise in the genetic manipulation of ES cells and the production of iPS cells, we are developing plans for a new scientific programme in stem cells and cellular phenotyping [SCCP]. The programme will have two major components – a resource of stem cells/iPS cells and a high-throughput cellular phenotyping platform.
We are seeking self-motivated and enthusiastic researchers with an undergraduate degree in a biological science and cell culture expertise to support the programme. The roles will form a key part of our new high-throughput core facility, generating, maintaining and genetically manipulating large numbers of high quality stem cells and differentiated cell lines. These cell lines will be generated from human and mouse tissues before being passed to other teams for phenotyping at the genetic and cellular level.
The post holders will be involved in running established cellular assays on stem cells and differentiated cell lines as part of a high throughput pipeline made up of interacting teams. Specifically, they will prepare cells, run the assays and ensure samples are analysed appropriately using microscopy and image capture. The high volumes of material mean that processes will be automated where possible. New techniques and processes will be developed by other teams and implemented by the postholders.
Essential Skills
Our high-throughput pipeline requires absolute accuracy, attention to detail and concentration for tracking and processing of large numbers of cell clones. BSc in Biology or equivalent experience in laboratory work including running routine cellular analyses is essential. Good manual dexterity is vital for developing excellent sterile technique. Good organisational and communication skills will be required to manage own workload and to work effectively within a multidisciplinary team. This role is predominantly laboratory based and whilst training will be given, previous laboratory experience is essential.
Ideal Skills
Ideally you will be a team player looking for the opportunity to join an exciting pipeline generating a large high quality international resource. Previous experience in growing pluripotent stem cells preferably of human origin will be an advanatge as well as familiarity with standard computer software programs for molecular biology applications, experience with data entry, sample tracking and high-throughput applications.
Benefits
The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk,
To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk, to register and apply on line.]
Salary range £17,188 to £21,914 per annum dependent on experience.
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