Salary range £17188 to £21914 pa dependent on experience
The Wellcome Trust Sanger Institute, based south of Cambridge, is one of the world’s leading genomic research centres funded primarily by the Wellcome Trust. Our mission is to use genome sequences to advance understanding of the biology of humans and pathogens in order to improve human health.
With the completion of the human and mouse genome sequences, attention is now turning to the functional analysis of genes in mammals. The Mouse Genetics Project (MGP), a flagship project of the Sanger Institute, aims to generate more than 1000 mutant strains of mice over the next 5 years and characterize them through a broad primary screen followed by detailed secondary phenotyping of selected mutants of interest. The mutant strains and the primary phenotypic data we produce are openly available to the scientific community (http://www.sanger.ac.uk/mouseportal/). This project forms an essential component of a larger effort at the Institute to identify genes that are critical for normal mammalian development and to generate animal models of human disease.
We are looking for an enthusiastic and committed Research Assistant to join our exciting programme of research. The day to day activities of the role cover a broad spectrum of activities including:
•Phenotypic assessment at key gestational stages using a range of methods
•Reporter gene expression analysis in adults and embryos
•Histological analysis of biobanked samples as part of standard primary phenotyping or as specialised secondary phenotyping projects
•In-life characterisation of the mice using a broad range of phenotyping assays designed to identify morphological, metabolic, skeletal, sensory and behavioural abnormalities
Detailed record keeping is required, as is contribution to data analysis, review and reporting.
Essential Skills
BSc or equivalent experience
Basic general understanding of the scientific concepts and principles and associated practical techniques relevant to anatomy, histopathology and/or developmental biology
Adaptable, enthusiastic and approachable
Team oriented
Highly organised
Quality orientated
Able to work under pressure
Methodical and thorough approach with strong attention to detail
Effective communication skills
Strong computing skills
Ideal Skills
Previous experience working in a histology or developmental biology lab
Experience handling mice
Experience of mouse necropsies
Benefits
The Institute has excellent purpose built facilities on the Genome Campus, Hinxton on the outskirts of Cambridge. We offer a comprehensive range of benefits including a final salary pension scheme and excellent on-site facilities. Further details can be found on our website https://jobs.sanger.ac.uk
http://twitter.com/sangerinstjobs/
Other information
Informal enquiries may be made to Jacqui White (MGP Phenotyping Manager) – email: jkw@sanger.ac.uk tel: 01223 495346
To submit your CV and apply for this job please go to https://jobs.sanger.ac.uk, to register and apply
Closing date 20th July 2012