Research Scientist or Research Associate - Manufacturing - London
Research Scientist or Research Associate - Manufacturing
(Viral Vector and T Cell Processing GMP & Development)
Grade: Research Scientist or Research Associate
Reports to: Initially to the Director, Process Development
Hours: Full time
Salary range: Competitive salary and benefits package, including a pension scheme, life assurance, group income protection and private medical insurance
Location: London, W12 and Greater London area
Autolus is a private biopharmaceutical company, focused on the development and commercialisation of engineered T-cell immunotherapy products based on its proprietary T-cell programming technology. The company has a differentiated product pipeline coupled with a strong technology platform to ensure long-term sustainability. Autolus has strong financial backing and the ambition to become a global leader in T-cell therapy for treatment of cancer patients.
Founded on the work of Dr Martin Pule, an academic clinical haematologist and thought-leader in T-cell engineering, the Autolus team is developing CAR T-cell products that can specifically and safely destroy malignant cells and provide long-term protection from recurrence of the tumour. We are currently scaling up our in-house capabilities in research, pre-clinical development, manufacturing and clinical development. We are building a leading biotechnology company with the ambition to be a leader of a revolution in medicine in which life-threatening diseases are treated by a patient’s own cells. This is a fantastic opportunity to join a fast-moving, innovative company that’s going places, and to make a real impact from early on.
Autolus was founded in 2014 by Syncona Partners LLP and UCL Business PLC, the wholly-owned technology transfer company of University College London. Established in 2012, Syncona is a subsidiary of the Wellcome Trust.
We are look for a bright, enthusiastic Research Scientist or Research Associate (depending on level of experience and qualifications) in our state-of-the-art laboratories in West London to join a manufacturing team committed to delivering high quality products for use in Autolus clinical trial programmes. Whilst these roles will be based in the Autolus laboratories in West London, there will also be a requirement to work within established manufacturing partner facilities in the Greater London area. You will be motivated and highly organised with knowledge of range of biopharmaceutical and cell-based techniques and an understanding of and familiarity with cGMP regulations, as well as an ability to work to a high standard. Previous experience working in a GMP environment is highly desirable.
- Participate in the manufacture of viral vectors and cell-based products
- Assist in the maintenance of a laboratory environment suitable for the manufacture of sterile biopharmaceutical products
- Perform duties according to current Good Manufacturing Practice (cGMP)
- Create and maintain compliant process documentation
- Work with external service providers
- Supervise staff as necessary
- Compile batch documentation and certify accuracy
- Oversee equipment maintenance programmes
- Design and implement training programmes
- Design and implement internal audit programmes
- Any other duties as required following consultation with the post holder
- The post-holder will be responsible for adhering to all health and safety guidance, provided by the Company
Demonstrated skills and competencies
E – Essential
P - Preferred
- Directly relevant biotechnology or pharmaceutical industry experience (E)
- Experience of working in a busy laboratory environment is desirable, although full training will be given (P)
- Previous experience working in a GMP environment is highly desirable (P)
- A BSc/MSc or equivalent in Biology/Biochemistry or related discipline - Research Associate level (E).
- An PhD in Biology/Biochemistry or related discipline - Research Scientist level (E)
- Familiarity with a range of biopharmaceutical and cell-based techniques (E)
- Understanding of and familiarity with cGMP regulations (E)
- Strong verbal and written communication skills (E)
- Good attention to detail and ability to accurately follow SOPs (E)
- Ability to identify and implement solutions (E)
- Commitment to high quality work (E)
- Familiarity with cGMP guidelines is highly desirable (P)
To apply, please click on the 'Apply' button.
We expect to have a high number of applicants for this post and we would advise that you apply quickly as we may close the advert early.