Sequence Bioanalyst - Bioinformatics, London based

London, England
Sep 30, 2016
Oct 28, 2016
Jade Page
Result Type
Position Type
Full Time

Sequence Bioanalyst - Bioinformatics, London based

IVD (In-Vitro Diagnostics), Next Generation Sequencing, Statistical Analysis, Molecular Biologist

Paramount Recruitment is currently working with an innovative organisation in London who are working with us to grow their new Bioinformatics team. This company have been established for almost 15 years and have a very talented team based in the heart of London.

This company is a front runner in next generation sequencing, developing a new product line that will transform medical diagnosis. It is a challenging time in the field and we are excited to announce a new position for a Sequence Bioanalyst to join this group at the beginning of their growth.


*Gather and analyse medical algorithms, translate them into high-level Assay need.
*Converting clinical questions into a list of Genomic targets for the diagnostic platform
*Designing and documenting molecular assays for real-time PCR and targeted sequencing assays.
*Understanding the Biology of each target (from physiology to molecular basis)
*Use standard BioInformatics tools (i.e internal BioInformatics servers and stand-alone sequence analysis softwares)
*Building, curating and maintaining target-specific internal sequence databanks
*Interpreting results using the in house software, analysing DNA, extracting data
*Actively contributing to the development of the bioinformatics pipeline component of the company's targeted sequencing solution
*Linking molecular and BioInformatics solutions to high level diagnostics results
*Design Assays, order oligonucleotides and evaluate the residual technical risks
*Actively promote scientific interactions within the BioInformatics team by representing both clinician needs as well as a biologist point of view
*Participating in relevant clinical diagnostics and regulatory forums

Experience Required:

*Educated to degree level in biology, genetics and sequence analysis
*Solid experience of designing and developing molecular biology assays (NGS, NAAT) using advanced bioinformatics tools
*Good DNA analysis experience
*Good knowledge of both generalist and specialised sequence repositories (e.g. Genbank, FDA-Argos) and their use in clinical development context
*Knowledge of the regulatory requirements for the design and development of IVD assays
*Ideally coming from a multidisciplinary environment with exceptional communication skills
*Experience with oligonucleotide chemistry, surface chemistry and enzymology

There is a competitive salary on offer for this role in addition to a great range of benefits. This is a great opportunity to join a team at the start of their development and really have a huge impact on their product and its results.

We would love to hear from you if you meet the requirements, please don't hesitate to contact Jade on +44 121 616 3472 for more information on this role.

Keywords: Bioanalyst, Sequencing, Statistics, Bioinformatics, Biostatistician, NGS, Next Generation Sequencing, IVD, Medical Devices, Diagnostics, London

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