Scientific Director, Group B Streptococcal Vaccine Project - Seattle, WA

Seattle, WA
Competitive salary
Oct 06, 2016
Dec 01, 2016
Result Type
Position Type
Full Time

Scientific Director, Group B Streptococcal Vaccine Project
Job Location: 
Seattle, Washington, United States
Company Location: United States, Seattle
Position Type: Full-Time/Regular

PATH is currently recruiting for a Scientific Director, Group B Streptococcal (GBS) Vaccine Project, who will have leadership and management responsibilities for overseeing animal models and biological assays, and clinical assays and immune analytics that support GBS vaccine development and introduction.
PATH is an international organization that drives transformative innovation to save lives and improve health, especially among women and children. We accelerate innovation across five platforms-vaccines, drugs, diagnostics, devices, and system and service innovations-that harness our entrepreneurial insight, scientific and public health expertise, and passion for health equity. By mobilizing partners around the world, we take innovation to scale, working alongside countries primarily in Africa and Asia to tackle their greatest health needs. Together, we deliver measurable results that disrupt the cycle of poor health.
PATH’s work on vaccine development and introduction encompasses activities including discovery, preclinical development, clinical research and development, process development and manufacturing, regulatory and vaccine introduction. Over 25 candidates and vaccines are currently in our portfolio in the following disease areas- Malaria, Enteric and Diarrheal Diseases, Polio, Respiratory Tract Infections and Meningitis, HPV and Vector-borne viral diseases (e.g., Japanese Encephalitis) - and in the cross-cutting area of Maternal Immunization.
Respiratory Infections & Maternal Immunizations (RIMI) is a vaccine development and introduction program with the mission to accelerate the development and introduction of vaccines and associated technologies and ensure their affordability, availability and accessibility in developing countries. To accomplish its mission, RIMI is identifying the most promising vaccines and associated technologies and implementing targeted partnerships across all sectors. RIMI works with government, industry, and academic partners in development, clinical testing, and preparing for the introductions of a portfolio of vaccines. With later-stage vaccine candidates, RIMI manages clinical trial sites in various countries and works with a range of stakeholders to ensure the highest quality trails that produce crucial information for public health decision making.
The Group B Streptococcal Vaccine Project (GBS) Vaccine Project resides within RIMI. The Scientific Director, GBS Vaccine Project reports to the Director of Pneumococcal, Polyvalent Meningococcal and GBS Vaccine Projects within RIMI.
Specific responsibilities include:  

  • Implement the development of the GBS Vaccine Project consistent with PATH’s mission, values, and policies and RIMI’s vaccine development goals and objectives.
  • In coordination with partners, assess and facilitate the development of the GBS vaccine candidate. Interpret scientific data from the GBS vaccine development project and work with partners to implement further development studies.
  • Provide strategic oversight and technical guidance for designing, planning, monitoring and evaluating and reporting (including publishing) results for animal models and biological assays; clinical assays and immune analytics that support GBS vaccine development.
  • Manage partner and contract relationships related to timely completion of process development and manufacturing activities.
  • Oversee annual work plans and compliance with all donor requirements.
  • Foster strategic linkages between the GBS Vaccine Project and RIMI’s other vaccine development projects to maximize RIMI’s experience and use of resources to develop and introduce new vaccines as part of comprehensive strategies to prevent and control respiratory infections.
  • Present data at scientific meetings and represent PATH at international, regional and national meetings. 

Required Experience 

  • Advanced degree in microbiology, immunology or related field required.
  • A proven experience in vaccine discovery and development; clinical trial experience desirable.
  • Experience in a leadership role in a vaccine industry or product development/introduction setting (or an equivalent combination of education and experience).
  • Experience in research, development and introduction of vaccines within the pharmaceutical industry, academia or equivalent.
  • Experience in planning, design, and execution of preclinical vaccine studies and the interpretation of experimental data.
  • Knowledge of biological process/analytical/formulation development, process scale-up, commercial manufacturing and quality control.
  • Experience in immunological assay standardization, qualification and validation desirable.
  • A high degree of initiative, independent judgment and resourcefulness. 
  • Working knowledge of regulatory requirements for licensing of biological products.
  • Demonstrated experience in collaborative environments and success in achieving milestone results within them.
  • Demonstrated written and verbal presentation skills.
  • International experience is highly desirable.
  • Ability to travel up to 25%.

Must have legal authorization to work in the United States. 

To apply, please click on the ‘Apply’ button

PATH is dedicated to building an inclusive workforce where diversity is valued.
PATH is an equal opportunity employer. Every qualified applicant will be considered for employment. PATH does not discriminate based on race, color, religion, gender, gender identity or orientation, genetic information, age, national origin, marital status, disability status, political ideology, military or protected veteran status, or any other characteristic protected by applicable federal, state, or local law.